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GLP-1 receptor agonists are a type of therapeutic that activates the GLP-1 receptors in various tissues, mimicking the effects of the naturally occurring hormone glucagon-like peptide-1 (GLP-1)

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According to NICE Technology Appraisal 875 (TA875), these criteria typically include a body mass index (BMI) of 35 kg/m² or above, or 32.5 kg/m² or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds, with at least one weight-related comorbidity